March 15, 2010

BREAST CANCER

Predictors of Tumor Progression During Neoadjuvant Chemotherapy in Breast Cancer

Abigail S. Caudle, Ana M. Gonzalez-Angulo, Kelly K. Hunt, Ping Liu, Lajos Pusztai, W. Fraser Symmans, Henry M. Kuerer, Elizabeth A. Mittendorf, Gabriel N. Hortobagyi, and Funda Meric-Bernstam
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.25.3286 [Abstract] [PDF]  

BREAST CANCER

Identification of Subtypes in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer Reveals a Gene Signature Prognostic of Outcome

Johan Staaf, Markus Ringnér, Johan Vallon-Christersson, Göran Jönsson, Pär-Ola Bendahl, Karolina Holm, Adalgeir Arason, Haukur Gunnarsson, Cecilia Hegardt, Bjarni A. Agnarsson, Lena Luts, Dorthe Grabau, Mårten Fernö, Per-Olof Malmström, Oskar Th. Johannsson, Niklas Loman, Rosa B. Barkardottir, and Åke Borg
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.22.8775 [Abstract] [PDF] [Data Supplements]  

DIAGNOSIS IN ONCOLOGY

Retroperitoneal Diffuse Large B-Cell Lymphoma Presenting As Pseudoachalasia

Danielle M. Pastor, Ashley D. Eggers, Joseph J. Drabick, Thomas P. Loughran, Michael G. Bayerl, and Timothy R. Shope
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.25.8715 [Abstract] [PDF]  

EDITORIALS

HER2 Signatures in Breast Cancer: Ready to Go to Print?

Pieter J.A. Eichhorn and José Baselga
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.26.7146 [Abstract] [PDF]  

EPIDEMIOLOGY

Functional Promoter -1271G>C Variant of HSPB1 Predicts Lung Cancer Risk and Survival

Huan Guo, Yun Bai, Ping Xu, Zhibin Hu, Li Liu, Fang Wang, Guangfu Jin, Feng Wang, Qifei Deng, Yixiao Tu, Maohui Feng, Daru Lu, Hongbing Shen, and Tangchun Wu
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.24.4954 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

Multicenter Phase II Study of Everolimus in Patients With Previously Treated Metastatic Gastric Cancer

Toshihiko Doi, Kei Muro, Narikazu Boku, Yasuhide Yamada, Tomohiro Nishina, Hiroya Takiuchi, Yoshito Komatsu, Yasuo Hamamoto, Nobutsugu Ohno, Yoshie Fujita, Matthew Robson, and Atsushi Ohtsu
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.26.2923 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Single-Agent Gemcitabine As First-Line Treatment of Patients With Advanced Pancreatic Cancer: The GIP-1 Study

Giuseppe Colucci, Roberto Labianca, Francesco Di Costanzo, Vittorio Gebbia, Giacomo Cartenì, Bruno Massidda, Elisa Dapretto, Luigi Manzione, Elena Piazza, Mirella Sannicolò, Marco Ciaparrone, Luigi Cavanna, Francesco Giuliani, Evaristo Maiello, Antonio Testa, Paolo Pederzoli, Massimo Falconi, Ciro Gallo, Massimo Di Maio, and Francesco Perrone
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.25.4433 [Abstract] [PDF] [Publisher's Note]  

GENITOURINARY CANCER

Prognostic Factors in Patients With Advanced Transitional Cell Carcinoma of the Urothelial Tract Experiencing Treatment Failure With Platinum-Containing Regimens

Joaquim Bellmunt, Toni K. Choueiri, Ronan Fougeray, Fabio A.B. Schutz, Yacine Salhi, Eric Winquist, Stéphane Culine, Hans von der Maase, David J. Vaughn, and Jonathan E. Rosenberg
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.25.4599 [Abstract] [PDF]  

PEDIATRIC ONCOLOGY

Psychological Outcomes and Health Beliefs in Adolescent and Young Adult Survivors of Childhood Cancer and Controls

Anne E. Kazak, Branlyn Werba DeRosa, Lisa A. Schwartz, Wendy Hobbie, Claire Carlson, Richard F. Ittenbach, Jun J. Mao, and Jill P. Ginsberg
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.25.9564 [Abstract] [PDF]  

PEDIATRIC ONCOLOGY

Predicting Adverse Events in Children With Fever and Chemotherapy-Induced Neutropenia: The Prospective Multicenter SPOG 2003 FN Study

Roland A. Ammann, Nicole Bodmer, Andreas Hirt, Felix K. Niggli, David Nadal, Arne Simon, Hulya Ozsahin, Udo Kontny, Thomas Kühne, Maja Beck Popovic, Annette Ridolfi Lüthy, and Christoph Aebi
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.25.8988 [Abstract] [PDF]  

PEDIATRIC ONCOLOGY

Gene Expression–Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia

Silvia Bresolin, Marco Zecca, Christian Flotho, Luca Trentin, Andrea Zangrando, Laura Sainati, Jan Stary, Barbara de Moerloose, Henrik Hasle, Charlotte M. Niemeyer, Geertruy te Kronnie, Franco Locatelli, and Giuseppe Basso
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.24.4426 [Abstract] [PDF]  

SPECIAL ARTICLES

Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

Patrick Y. Wen, David R. Macdonald, David A. Reardon, Timothy F. Cloughesy, A. Gregory Sorensen, Evanthia Galanis, John DeGroot, Wolfgang Wick, Mark R. Gilbert, Andrew B. Lassman, Christina Tsien, Tom Mikkelsen, Eric T. Wong, Marc C. Chamberlain, Roger Stupp, Kathleen R. Lamborn, Michael A. Vogelbaum, Martin J. van den Bent, and Susan M. Chang
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.26.3541 [Abstract] [PDF]  

THORACIC ONCOLOGY

Surgery With or Without Preoperative Paclitaxel and Carboplatin in Early-Stage Non–Small-Cell Lung Cancer: Southwest Oncology Group Trial S9900, an Intergroup, Randomized, Phase III Trial

Katherine M.W. Pisters, Eric Vallières, John J. Crowley, Wilbur A. Franklin, Paul A. Bunn Jr, Robert J. Ginsberg, Joe B. Putnam Jr, Kari Chansky, and David Gandara
JCO published online March 15, 2010, DOI:10.1200/JCO.2009.26.1685 [Abstract] [PDF]  

March 8, 2010

BREAST CANCER

Prediction of Risk of Distant Recurrence Using the 21-Gene Recurrence Score in Node-Negative and Node-Positive Postmenopausal Patients With Breast Cancer Treated With Anastrozole or Tamoxifen: A TransATAC Study

Mitch Dowsett, Jack Cuzick, Christopher Wale, John Forbes, Elizabeth A. Mallon, Janine Salter, Emma Quinn, Anita Dunbier, Michael Baum, Aman Buzdar, Anthony Howell, Roberto Bugarini, Frederick L. Baehner, and Steven Shak
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.24.4798 [Abstract] [PDF]  

CLINICAL PRACTICE

Review of Adherence-Related Issues in Adolescents and Young Adults With Cancer

Phyllis Butow, Susan Palmer, Ahna Pai, Belinda Goodenough, Tim Luckett, and Madeleine King
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.22.2802 [Abstract] [PDF]  

CORRESPONDENCE

Reply to M.H. Tan et al

Hyeong-Gon Moon, Wonshik Han, and Dong-Young Noh
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.27.0991 [Abstract] [PDF]  

CORRESPONDENCE

Association Between Being Underweight and Outcomes in Breast Cancer: Alternative Explanations

Min-Han Tan, Nicholas Qijie Leo, En Yun Loy, Wei-Yen Lim, and Kee Seng Chia
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.27.0363 [Abstract] [PDF]  

CORRESPONDENCE

Bevacizumab and Recurrent Malignant Gliomas: A European Perspective

Wolfgang Wick, Michael Weller, Martin van den Bent, and Roger Stupp
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.26.9027 [Abstract] [PDF] [Publisher's Note]  

EDITORIAL

If Histology Matters...

Thomas E. Stinchcombe, Juneko E. Grilley-Olson, and Mark A. Socinski
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.27.1247 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

Pancreatic Proteolytic Enzyme Therapy Compared With Gemcitabine-Based Chemotherapy for the Treatment of Pancreatic Cancer

John A. Chabot, Wei-Yann Tsai, Robert L. Fine, Chunxia Chen, Carolyn K. Kumah, Karen A. Antman, and Victor R. Grann
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.22.8429 [Abstract] [PDF] [Publisher's Note]  

HEMATOLOGIC MALIGNANCIES

Relapse and Late Mortality in 5-Year Survivors of Myeloablative Allogeneic Hematopoietic Cell Transplantation for Chronic Myeloid Leukemia in First Chronic Phase

John M. Goldman, Navneet S. Majhail, John P. Klein, Zhiwei Wang, Kathleen A. Sobocinski, Mukta Arora, Mary M. Horowitz, and J. Douglas Rizzo
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.26.7757 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Risk-Adapted Dose-Dense Immunochemotherapy Determined by Interim FDG-PET in Advanced-Stage Diffuse Large B-Cell Lymphoma

Craig H. Moskowitz, Heiko Schöder, Julie Teruya-Feldstein, Camelia Sima, Alexia Iasonos, Carol S. Portlock, David Straus, Ariela Noy, Maria L. Palomba, Owen A. O'Connor, Steven Horwitz, Sarah A. Weaver, Jessica L. Meikle, Daniel A. Filippa, James F. Caravelli, Paul A. Hamlin, and Andrew D. Zelenetz
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.26.5942 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Phase III Placebo-Controlled Trial of Denileukin Diftitox for Patients With Cutaneous T-Cell Lymphoma

H. Miles Prince, Madeleine Duvic, Ann Martin, Wolfram Sterry, Chalid Assaf, Yijun Sun, David Straus, Mark Acosta, and Andres Negro-Vilar
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.26.2386 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Comparison of Cladribine Plus Cyclophosphamide With Fludarabine Plus Cyclophosphamide As First-Line Therapy for Chronic Lymphocytic Leukemia: A Phase III Randomized Study by the Polish Adult Leukemia Group (PALG-CLL3 Study)

Tadeusz Robak, Krzysztof Jamroziak, Joanna Gora-Tybor, Beata Stella-Holowiecka, Lech Konopka, Bernadetta Ceglarek, Krzysztof Warzocha, Ilona Seferynska, Jarosaw Piszcz, Malgorzata Calbecka, Aleksandra Kostyra, Jadwiga Dwilewicz-Trojaczek, Anna Dmoszyñska, Krystyna Zawilska, Andrzej Hellmann, Andrzej Zdunczyk, Stanislaw Potoczek, Magdalena Piotrowska, Krzysztof Lewandowski, and Jerzy Z. Blonski
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.25.9630 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Phase I/II Study of Combination Therapy With Sorafenib, Idarubicin, and Cytarabine in Younger Patients With Acute Myeloid Leukemia

Farhad Ravandi, Jorge E. Cortes, Daniel Jones, Stefan Faderl, Guillermo Garcia-Manero, Marina Y. Konopleva, Susan O'Brien, Zeev Estrov, Gautam Borthakur, Deborah Thomas, Sherry R. Pierce, Mark Brandt, Anna Byrd, B. Nebiyou Bekele, Keith Pratz, Rajyalakshmi Luthra, Mark Levis, Michael Andreeff, and Hagop M. Kantarjian
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.25.4888 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Effect of Age on Outcome of Reduced-Intensity Hematopoietic Cell Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission or With Myelodysplastic Syndrome

Brian L. McClune, Daniel J. Weisdorf, Tanya L. Pedersen, Gisela Tunes da Silva, Martin S. Tallman, Jorge Sierra, John DiPersio, Armand Keating, Robert P. Gale, Biju George, Vikas Gupta, Theresa Hahn, Luis Isola, Madan Jagasia, Hillard Lazarus, David Marks, Richard Maziarz, Edmund K. Waller, Chris Bredeson, and Sergio Giralt
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.25.4821 [Abstract] [PDF]  

PALLIATIVE AND SUPPORTIVE CARE

Are the Most Distressing Concerns of Patients With Inoperable Lung Cancer Adequately Assessed? A Mixed-Methods Analysis

Carol Tishelman, Malin Lövgren, Eva Broberger, Katarina Hamberg, and Mirjam A.G. Sprangers
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.23.3403 [Abstract] [PDF]  

PALLIATIVE AND SUPPORTIVE CARE

Experiences and Attitudes of Patients With Terminal Cancer and Their Family Caregivers Toward the Disclosure of Terminal Illness

Young Ho Yun, Yong Chol Kwon, Myung Kyung Lee, Woo Jin Lee, Kyung Hae Jung, Young Rok Do, Samyong Kim, Dae Seog Heo, Jong Soo Choi, and Sang Yoon Park
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.22.9658 [Abstract] [PDF]  

PALLIATIVE AND SUPPORTIVE CARE

Role of Palliative Care in Adolescent and Young Adult Oncology

Simon Wein, Shlomit Pery, and Alona Zer
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.22.4543 [Abstract] [PDF]  

PEDIATRIC ONCOLOGY

Benefits of the Intermittent Use of 6-Mercaptopurine and Methotrexate in Maintenance Treatment for Low-Risk Acute Lymphoblastic Leukemia in Children: Randomized Trial From the Brazilian Childhood Cooperative Group—Protocol ALL-99

Silvia R. Brandalise, Vitória R. Pinheiro, Simone S. Aguiar, Eduardo I. Matsuda, Rosemary Otubo, José A. Yunes, Waldir V. Pereira, Eny G. Carvalho, Lilian M. Cristofani, Marcelo S. Souza, Maria L. Lee, Jane A. Dobbin, Maria S. Pombo-de-Oliveira, Luiz F. Lopes, Katharina N.T. Melnikoff, Algemir L. Brunetto, Luiz G. Tone, Carlos A. Scrideli, Vera L.L. Morais, and Marcos B. Viana
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.25.6115 [Abstract] [PDF]  

REVIEW ARTICLES

Practical Grading System for Evaluating Cisplatin Ototoxicity in Children

Kay W. Chang and Nina Chinosornvatana
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.24.4228 [Abstract] [PDF]  

STATISTICS IN ONCOLOGY

Comparison of Error Rates in Single-Arm Versus Randomized Phase II Cancer Clinical Trials

Hui Tang, Nathan R. Foster, Axel Grothey, Stephen M. Ansell, Richard M. Goldberg, and Daniel J. Sargent
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.25.5489 [Abstract] [PDF]  

THORACIC ONCOLOGY

Phase III Study of Carboplatin and Paclitaxel Alone or With Sorafenib in Advanced Non–Small-Cell Lung Cancer

Giorgio Scagliotti, Silvia Novello, Joachim von Pawel, Martin Reck, José Rodrigues Pereira, Michael Thomas, José Elias Abrão Miziara, Beatrix Balint, Filippo De Marinis, Alan Keller, Osvaldo Arén, Maria Csollak, Istvan Albert, Carlos Henrique Barrios, Francesco Grossi, Maciej Krzakowski, Lisa Cupit, Frank Cihon, Sandra DiMatteo, and Nasser Hanna
JCO published online March 8, 2010, DOI:10.1200/JCO.2009.26.1321 [Abstract] [PDF]  

March 1, 2010

ART OF ONCOLOGY

Our Version of Normal

William A. Wood
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.27.3201 [Abstract] [PDF]  

ART OF ONCOLOGY

Art Informs Medicine

Celia Engel Bandman
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.27.2708 [Abstract] [PDF]  

ART OF ONCOLOGY

Hope and Noncurative Chemotherapies: Which Affects the Other?

Serge Daneault, Dominique Dion, Claude Sicotte, Louise Yelle, Suzanne Mongeau, Véronique Lussier, Manon Coulombe, and Pierre Paillé
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.8425 [Abstract] [PDF]  

BIOLOGY OF NEOPLASIA

Translating Gene Expression into Clinical Care: Sarcomas As a Paradigm

Torsten O. Nielsen and Robert B. West
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.1917 [Abstract] [PDF]  

BREAST CANCER

Comparable Survival Between pN0 Breast Cancer Patients Undergoing Sentinel Node Biopsy and Extensive Axillary Dissection: A Report From the Korean Breast Cancer Society

Hyeong-Gon Moon, Wonshik Han, and Dong-Young Noh
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.9226 [Abstract] [PDF]  

BREAST CANCER

Breast Cancer Subtypes and the Risk of Local and Regional Relapse

K. David Voduc, Maggie C.U. Cheang, Scott Tyldesley, Karen Gelmon, Torsten O. Nielsen, and Hagen Kennecke
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.24.9284 [Abstract] [PDF]  

COMMENTS AND CONTROVERSIES

Neutrophil Count in African-Americans: Lowering the Target Cutoff to Initiate or Resume Chemotherapy?

Matthew M. Hsieh, John F. Tisdale, Griffin P. Rodgers, Neal S. Young, Edward L. Trimble, and Richard F. Little
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.24.3881 [Abstract] [PDF]  

CORRESPONDENCE

Reply to T. Grenader et al

Joseph A. Sparano
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.9514 [Abstract] [PDF]  

CORRESPONDENCE

What Is the Right Way to Administer Pegylated Liposomal Doxorubicin in Breast Cancer Therapy?

Tal Grenader and Alberto Gabizon
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.8052 [Abstract] [PDF]  

CORRESPONDENCE

Reply to P. Laneuville et al

Carlo Gambacorti-Passerini, Rocco Piazza, Pietro Perini, Roberta Rostagno, and Sara Redaelli
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.5371 [Abstract] [PDF]  

CORRESPONDENCE

Reply to M.L. Lanthier et al

Charles L. Bennett and Jonathan R. Nebeker
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.5330 [Abstract] [PDF]  

CORRESPONDENCE

Comparative In Vitro Cellular Data Alone Are Insufficient to Predict Clinical Responses and Guide the Choice of BCR-ABL Inhibitor for Treating Imatinib-Resistant Chronic Myeloid Leukemia

Pierre Laneuville, Clifford DiLea, Ophelia Q.P. Yin, Richard C. Woodman, Jürgen Mestan, and Paul W. Manley
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.4945 [Abstract] [PDF]  

CORRESPONDENCE

Accelerated Approval and Oncology Drug Development Timelines

Michael L. Lanthier, Rajeshwari Sridhara, John R. Johnson, Ann Farrell, Patricia Keegan, Robert Justice, and Richard Pazdur
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.2121 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Mixed Response in Interim Positron Emission Tomography/Computed Tomography Leads to Detection of a Gastrointestinal Stromal Tumor in a Patient With Mediastinal Diffuse Large B-Cell Lymphoma

Cord Rehmsmeier, Torsten Kessler, Steffen Koschmieder, Matthias Ross, Matthias Weckesser, Johannes Wessling, Gabriele Koehler, and Wolfgang E. Berdel
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.8848 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Diffuse Osteosclerosis Complicating Hairy Cell Leukemia

Rock Leung, David Lopes, Clarence Lam, Kit-Fai Wong, Annie W.C. Kung, and Yok-Lam Kwong
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.24.7601 [Abstract] [PDF]  

EDITORIALS

Molecular Predictors of Locoregional Recurrence in Breast Cancer: Ready for Prime Time?

Bruce G. Haffty and Thomas A. Buchholz
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.27.1080 [Abstract] [PDF]  

EDITORIALS

Improving Local Control in Rectal Cancer: Radiation Sensitizers or Radiation Dose?

Joel E. Tepper and Andrew Z. Wang
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.9787 [Abstract] [PDF]  

EDITORIALS

Critical Need for International Consensus on Ototoxicity Assessment Criteria

Edward A. Neuwelt and Penelope Brock
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.7872 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

Clinical Scoring System to Predict Hepatocellular Carcinoma in Chronic Hepatitis B Carriers

Vincent Wai-Sun Wong, Stephen Lam Chan, Frankie Mo, Tung-Ching Chan, Herbert Ho-Fung Loong, Grace Lai-Hung Wong, Yanni Yan-Ni Lui, Anthony Tak-Cheung Chan, Joseph Jao-Yiu Sung, Winnie Yeo, Henry Lik-Yuen Chan, and Tony Shu-Kam Mok
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.2675 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

Comparison of Two Neoadjuvant Chemoradiotherapy Regimens for Locally Advanced Rectal Cancer: Results of the Phase III Trial ACCORD 12/0405-Prodige 2

Jean-Pierre Gérard, David Azria, Sophie Gourgou-Bourgade, Isabelle Martel-Laffay, Christophe Hennequin, Pierre-Luc Etienne, Véronique Vendrely, Eric François, Guy de La Roche, Olivier Bouché, Xavier Mirabel, Bernard Denis, Laurent Mineur, Jean-François Berdah, Marc André Mahé, Yves Bécouarn, Olivier Dupuis, Gérard Lledo, Christine Montoto-Grillot, and Thierry Conroy
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.8376 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

Prognostic Value of Changes in Health-Related Quality of Life Scores During Curative Treatment for Esophagogastric Cancer

Therese Djärv, Chris Metcalfe, Kerry N.L. Avery, Pernilla Lagergren, and Jane M. Blazeby
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.23.5143 [Abstract] [PDF]  

GASTROINTESTINAL CANCER

⁹⁰Y-Edotreotide for Metastatic Carcinoid Refractory to Octreotide

David L. Bushnell Jr, Thomas M. O'Dorisio, M. Sue O'Dorisio, Yusuf Menda, Rodney J. Hicks, Eric Van Cutsem, Jean-Louis Baulieu, Francoise Borson-Chazot, Lowell Anthony, Al B. Benson, Kjell Oberg, Ashley B. Grossman, Mary Connolly, Hakim Bouterfa, Yong Li, Katherine A. Kacena, Norman LaFrance, and Stanislas A. Pauwels
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.22.8585 [Abstract] [PDF]  

GENITOURINARY CANCER

TI-CE High-Dose Chemotherapy for Patients With Previously Treated Germ Cell Tumors: Results and Prognostic Factor Analysis

Darren R. Feldman, Joel Sheinfeld, Dean F. Bajorin, Patricia Fischer, Stefan Turkula, Nicole Ishill, Sujata Patil, Manjit Bains, Lilian M. Reich, George J. Bosl, and Robert J. Motzer
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.1561 [Abstract] [PDF]  

GYNECOLOGIC CANCER

Potential Role of Lymphadenectomy in Advanced Ovarian Cancer: A Combined Exploratory Analysis of Three Prospectively Randomized Phase III Multicenter Trials

Andreas du Bois, Alexander Reuss, Philipp Harter, Eric Pujade-Lauraine, Isabelle Ray-Coquard, and Jacobus Pfisterer
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.3617 [Abstract] [PDF]  

GYNECOLOGIC CANCER

Outcomes of Fertility-Sparing Surgery for Stage I Epithelial Ovarian Cancer: A Proposal for Patient Selection

Toyomi Satoh, Masayuki Hatae, Yoh Watanabe, Nobuo Yaegashi, Osamu Ishiko, Shoji Kodama, Satoshi Yamaguchi, Kazunori Ochiai, Masashi Takano, Harushige Yokota, Yosuke Kawakami, Sadako Nishimura, Daiki Ogishima, Shunsuke Nakagawa, Hiroaki Kobayashi, Tanri Shiozawa, Toru Nakanishi, Toshiharu Kamura, Ikuo Konishi, and Hiroyuki Yoshikawa
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.24.8617 [Abstract] [PDF]  

HEALTH SERVICES AND OUTCOMES

Employment Among Survivors of Lung Cancer and Colorectal Cancer

Craig C. Earle, Yves Chretien, Carl Morris, John Z. Ayanian, Nancy L. Keating, Linnea A. Polgreen, Robert Wallace, Patricia A. Ganz, and Jane C. Weeks
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.24.7411 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Rituximab Plus Fludarabine and Cyclophosphamide Prolongs Progression-Free Survival Compared With Fludarabine and Cyclophosphamide Alone in Previously Treated Chronic Lymphocytic Leukemia

Tadeusz Robak, Anna Dmoszynska, Philippe Solal-Céligny, Krzysztof Warzocha, Javier Loscertales, John Catalano, Boris V. Afanasiev, Loree Larratt, Christian H. Geisler, Marco Montillo, Ilya Zyuzgin, Peter S. Ganly, Caroline Dartigeas, András Rosta, Jörg Maurer, Myriam Mendila, M. Wayne Saville, Nancy Valente, Michael K. Wenger, and Sergey I. Moiseev
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.26.4556 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Ofatumumab As Single-Agent CD20 Immunotherapy in Fludarabine-Refractory Chronic Lymphocytic Leukemia

William G. Wierda, Thomas J. Kipps, Jií Mayer, Stephan Stilgenbauer, Cathy D. Williams, Andrzej Hellmann, Tadeusz Robak, Richard R. Furman, Peter Hillmen, Marek Trneny, Martin J.S. Dyer, Swami Padmanabhan, Magdalena Piotrowska, Tomas Kozak, Geoffrey Chan, Randy Davis, Nedjad Losic, Joris Wilms, Charlotte A. Russell, and Anders Österborg
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.3187 [Abstract] [PDF]  

MELANOMA

Large Randomized Study of Thymosin 1, Interferon Alfa, or Both in Combination With Dacarbazine in Patients With Metastatic Melanoma

Michele Maio, Andrzej Mackiewicz, Alessandro Testori, Uwe Trefzer, Virginia Ferraresi, Jacek Jassem, Claus Garbe, Thierry Lesimple, Bernard Guillot, Pere Gascon, Katalin Gilde, Roberto Camerini, and Francesco Cognetti
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.5208 [Abstract] [PDF]  

PEDIATRIC ONCOLOGY

Psychological Distress in Adult Survivors of Childhood Cancer: The Swiss Childhood Cancer Survivor Study

Gisela Michel, Cornelia E. Rebholz, Nicolas X. von der Weid, Eva Bergstraesser, and Claudia E. Kuehni
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.23.4534 [Abstract] [PDF]  

REVIEW ARTICLES

Overall Survival and Post-Progression Survival in Advanced Breast Cancer: A Review of Recent Randomized Clinical Trials

Everardo D. Saad, Artur Katz, and Marc Buyse
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.5414 [Abstract] [PDF]  

SARCOMAS

Imatinib Mesylate in Advanced Dermatofibrosarcoma Protuberans: Pooled Analysis of Two Phase II Clinical Trials

Piotr Rutkowski, Martine Van Glabbeke, Cathryn J. Rankin, Wlodzimierz Ruka, Brian P. Rubin, Maria Debiec-Rychter, Alexander Lazar, Hans Gelderblom, Raf Sciot, Dolores Lopez-Terrada, Peter Hohenberger, Allan T. van Oosterom, and Scott M. Schuetze
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.25.7899 [Abstract] [PDF]  

THORACIC ONCOLOGY

Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer

Zhibin Hu, Xi Chen, Yang Zhao, Tian Tian, Guangfu Jin, Yongqian Shu, Yijiang Chen, Lin Xu, Ke Zen, Chenyu Zhang, and Hongbing Shen
JCO published online March 1, 2010, DOI:10.1200/JCO.2009.24.9342 [Abstract] [PDF]  

February 22, 2010

CORRESPONDENCE

Reply to P. Mathew

Emmanuel S. Antonarakis, Angelo M. De Marzo, Theodore L. DeWeese, and Michael A. Carducci
JCO published online February 22, 2010, DOI:10.1200/JCO.2009.27.1346 [Abstract] [PDF]  

CORRESPONDENCE

The Inflammatory Pathogenesis of Prostate Cancer and Celecoxib

Paul Mathew
JCO published online February 22, 2010, DOI:10.1200/JCO.2009.27.1098 [Abstract] [PDF]  

CORRESPONDENCE

Reply to U. De Giorgi et al

Wen Wee Ma
JCO published online February 22, 2010, DOI:10.1200/JCO.2009.26.8391 [Abstract] [PDF]  

CORRESPONDENCE

[¹⁸F]Fluorodeoxyglucose Positron Emission Tomography for Outcome Prediction of Mammalian Target of Rapamycin Inhibitor Therapy

Ugo De Giorgi and Dino Amadori
JCO published online February 22, 2010, DOI:10.1200/JCO.2009.26.6866 [Abstract] [PDF]  

CORRESPONDENCE

Reply to C. Cremolini et al

Bart Jacobs, Wendy De Roock, Hubert Piessevaux, Bart Biesmans, Jef De Schutter, Bart Claes, and Sabine Tejpar
JCO published online February 22, 2010, DOI:10.1200/JCO.2009.26.6809 [Abstract] [PDF]  

CORRESPONDENCE

Predictors of Benefit in Colorectal Cancer Treated With Cetuximab: Are We Getting "Lost in TranslationAL"?

Chiara Cremolini, Fotios Loupakis, Annamaria Ruzzo, Giuseppe Perrone, Eliana Rulli, Bruno Vincenzi, Giuseppe Tonini, Francesco Graziano, Andrea Onetti Muda, and Alfredo Falcone
JCO published online February 22, 2010, DOI:10.1200/JCO.2009.26.6148 [Abstract] [PDF]  

GENITOURINARY CANCER

Risk Factors for Prostate Cancer Detection After a Negative Biopsy: A Novel Multivariable Longitudinal Approach

Peter H. Gann, Angela Fought, Ryan Deaton, William J. Catalona, and Edward Vonesh
JCO published online February 22, 2010, DOI:10.1200/JCO.2008.20.3422 [Abstract] [PDF]  

February 16, 2010

CORRESPONDENCE

Reply to G. Sonpavde et al

Joaquim Bellmunt and Yacine Salhi
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.27.1338 [Abstract] [PDF]  

CORRESPONDENCE

Suggestions for Regulatory Agency Approval of Second-Line Systemic Therapy for Metastatic Transitional Cell Carcinoma

Guru Sonpavde, Jonathan E. Rosenberg, Noah M. Hahn, Matthew D. Galsky, Rick Bangs, Cora N. Sternberg, and Nicholas J. Vogelzang
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.27.1114 [Abstract] [PDF]  

CORRESPONDENCE

Reply to J. Livneh et al

Kristen McNiff
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.27.1015 [Abstract] [PDF]  

CORRESPONDENCE

Addressing Safety Issues of Health Care Personnel, Family Members, and the Environment

Jessica Livneh, Kent Waddington, and Jair Bar
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.9704 [Abstract] [PDF]  

CORRESPONDENCE

Reply to W. Wick et al

Henry S. Friedman, Michael D. Prados, Patrick Y. Wen, Tom Mikkelsen, David Schiff, Lauren E. Abrey, W. K. Alfred Yung, Nina Paleologos, Martin K. Nicholas, Randy Jensen, James Vredenburgh, Jane Huang, Maoxia Zheng, and Timothy Cloughesy
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.9472 [Abstract] [PDF]  

CORRESPONDENCE

Reply to L.C. Panasci and D.S.-W. Tan et al

Bente Holm, Anders Mellemgaard, Torsten Skov, and Birgit Guldhammer Skov
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.6833 [Abstract] [PDF]  

CORRESPONDENCE

Different Impact of Excision Repair Cross-Complementing Group 1 on Survival

Lawrence C. Panasci
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.6619 [Abstract] [PDF]  

CORRESPONDENCE

Truth About ERCC1 in Lung Cancer

Daniel S.-W. Tan, Quan-Sing Ng, Iain B.-H. Tan, Soon-Thye Lim, and Wan-Teck Lim
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.6270 [Abstract] [PDF]  

CORRESPONDENCE

Reply to M.A. Rosen et al

Shauna L. Hillman and Daniel J. Sargent
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.3426 [Abstract] [PDF]  

CORRESPONDENCE

Reply to S.L. Gomez et al

Matthew P. Goetz, Tanya L. Hoskin, Judy C. Boughey, and Amy C. Degnim
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.2972 [Abstract] [PDF]  

CORRESPONDENCE

Optimal Lesion Number for Evaluation of Tumor Response in Response Evaluation Criteria in Solid Tumors

Mark A. Rosen and Daniel Sullivan
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.2642 [Abstract] [PDF]  

CORRESPONDENCE

Increasing Mastectomy Rates for Early-Stage Breast Cancer? Population-Based Trends From California

Scarlett Lin Gomez, Daphne Lichtensztajn, Allison W. Kurian, Melinda L. Telli, Ellen T. Chang, Theresa H.M. Keegan, Sally L. Glaser, and Christina A. Clarke
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.26.1032 [Abstract] [PDF]  

HEMATOLOGIC MALIGNANCIES

Effect of Complete Remission and Responses Less Than Complete Remission on Survival in Acute Myeloid Leukemia: A Combined Eastern Cooperative Oncology Group, Southwest Oncology Group, and M.D. Anderson Cancer Center Study

Roland B. Walter, Hagop M. Kantarjian, Xuelin Huang, Sherry A. Pierce, Zhuoxin Sun, Holly M. Gundacker, Farhad Ravandi, Stefan H. Faderl, Martin S. Tallman, Frederick R. Appelbaum, and Elihu H. Estey
JCO published online February 16, 2010, DOI:10.1200/JCO.2009.25.1066 [Abstract] [PDF]  

February 1, 2010

ART OF ONCOLOGY

Life's Lessons Lost...and Learned

Reena George
JCO published online February 1, 2010, DOI:10.1200/JCO.2009.27.0413 [Abstract] [PDF]  

CORRESPONDENCE

Reply to M. Isik et al

Heikki Joensuu, Petri Bono, and Pirkko-Liisa Kellokumpu-Lehtinen
JCO published online February 1, 2010, DOI:10.1200/JCO.2009.27.3243 [Abstract] [PDF]  

CORRESPONDENCE

Two Important Determinants May Play a Role in the Success of the FinHer Trial

Metin Isik, Omer Dizdar, and Kadri Altundag
JCO published online February 1, 2010, DOI:10.1200/JCO.2009.27.2740 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Isolated Loss of Hormonal Receptors in Leptomeningeal Metastasis From Estrogen Receptor– and Progesterone Receptor–Positive Lobular Breast Cancer

Jai Grewal, Huadong Zhou, Rachel Factor, and Santosh Kesari
JCO published online February 1, 2010, DOI:10.1200/JCO.2009.25.3518 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Disseminated Tumor Embolism From Breast Cancer Leading to Multiorgan Failure

Daphne T. Tsoi, Corwyn Rowsell, Caitlin McGregor, Catherine M. Kelly, Sunil Verma, and Kathleen I. Pritchard
JCO published online February 1, 2010, DOI:10.1200/JCO.2009.25.1009 [Abstract] [PDF]  

January 11, 2010

BREAST CANCER

Association Between the 21-Gene Recurrence Score Assay and Risk of Locoregional Recurrence in Node-Negative, Estrogen Receptor–Positive Breast Cancer: Results From NSABP B-14 and NSABP B-20

Eleftherios P. Mamounas, Gong Tang, Bernard Fisher, Soonmyung Paik, Steven Shak, Joseph P. Costantino, Drew Watson, Charles E. Geyer Jr, D. Lawrence Wickerham, and Norman Wolmark
JCO published online January 11, 2010, DOI:10.1200/JCO.2009.23.7610 [Abstract] [PDF]  

BREAST CANCER

Prospective Multicenter Study of the Impact of the 21-Gene Recurrence Score Assay on Medical Oncologist and Patient Adjuvant Breast Cancer Treatment Selection

Shelly S. Lo, Patricia B. Mumby, John Norton, Karen Rychlik, Jeffrey Smerage, Joseph Kash, Helen K. Chew, Ellen R. Gaynor, Daniel F. Hayes, Andrew Epstein, and Kathy S. Albain
JCO published online January 11, 2010, DOI:10.1200/JCO.2008.20.2119 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Systemic Fibrinolysis Caused by Tissue Plasminogen Activator–Producing Metastatic Breast Cancer

Harris V.K. Naina, Mrinal M. Patnaik, Uzma A. Ali, Dong Chen, and Aneel A. Ashrani
JCO published online January 11, 2010, DOI:10.1200/JCO.2009.25.2502 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Hodgkin's Lymphoma Arising in a Patient With Hypersensitivity to Mosquito Bites: A Case Report

Silvia Park, Sunha Bahng, Eun Kyoung Kim, Sung Bum Park, Young Kyung Sung, Suk Jin Kim, Won Seog Kim, and Young Hyeh Ko
JCO published online January 11, 2010, DOI:10.1200/JCO.2009.25.0357 [Abstract] [PDF]  

DIAGNOSIS IN ONCOLOGY

Panhypopituitarism Secondary to Hypothalamic Involvement in a Woman With Diffuse Large B-Cell Lymphoma

Theresa W. Chan and Paul Hoskins
JCO published online January 11, 2010, DOI:10.1200/JCO.2009.24.9060 [Abstract] [PDF]  

EDITORIALS

Defining the Clinical Utility of Gene Expression Assays in Breast Cancer: The Intersection of Science and Art in Clinical Decision Making

Joseph A. Sparano and Lawrence J. Solin
JCO published online January 11, 2010, DOI:10.1200/JCO.2009.25.2882 [Abstract] [PDF]  

January 4, 2010

DIAGNOSIS IN ONCOLOGY

Superior Vena Cava Syndrome: A Presentation of Anaplastic Thyroid Carcinoma

Hema Padmanabhan
JCO published online January 4, 2010, DOI:10.1200/JCO.2009.24.8740 [Abstract] [PDF]  

December 14, 2009

DIAGNOSIS IN ONCOLOGY

Isolated Relapse of Acute Lymphoblastic Leukemia in the Epididymis: A Rare Sanctuary Site

Andrew E. Bourne, Robert O. Wayment, Thomas H. Tarter, and Patrick Hemmer
JCO published online December 14, 2009, DOI:10.1200/JCO.2009.23.8014 [Abstract] [PDF]  

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